Introduction to D-(-)-Asparagine Monohydrate
D-(-)-Asparagine Monohydrate, identified by its CAS number 2058-58-4, is a specialized compound recognized in the field of chemistry and pharmaceuticals. Known by various aliases such as D-Asparagin, H-D-Asn-OH·H2O, and (R)-2,4-Diamino-4-oxobutanoic acid, this amino acid derivative plays a crucial role in numerous applications. Its unique chemical structure and properties make it an essential ingredient in the synthesis of pharmaceutical intermediates, offering a foundation for innovative drug development.
This compound appears as a white powder crystal, boasting a purity level of at least 99.0%. With a molecular formula of C4H8N2O3 and a molecular weight of 132.118, it exhibits distinct physical characteristics that contribute to its utility across industries. In this article, we will explore its chemical properties, specifications, applications, and why it is a sought-after product from a reliable D-(-)-Asparagine Monohydrate manufacturer in China.
Chemical and Physical Properties
Understanding the chemical makeup of D-(-)-Asparagine Monohydrate is key to appreciating its functionality. It has a density of approximately 1.4±0.1 g/cm³, a boiling point of 438.0±40.0 °C at 760 mmHg, and a melting point of 280°C (decomposing). The compound’s flash point stands at 218.7±27.3 °C, with an exact mass of 132.053497 and a polar surface area (PSA) of 106.41000. Its LogP value of -1.51 indicates its hydrophilic nature, while the vapor pressure is negligible at 0.0±2.3 mmHg at 25°C, and its refractive index is 1.533.
These properties collectively ensure stability and compatibility in various chemical processes. For instance, the high melting point and decomposition temperature suggest that it can withstand significant thermal conditions, making it suitable for industrial applications where heat is involved. The specific rotation, ranging from -34.2 to -36.5°, further distinguishes its optical activity, a critical factor in pharmaceutical synthesis where chirality impacts efficacy.
Detailed Specifications
When sourced from a trusted D-(-)-Asparagine Monohydrate supplier in China, this compound meets stringent quality standards. Its assay confirms a minimum purity of 99.0%, ensuring high performance in its intended uses. The loss on drying ranges between 11.5% and 12.5%, reflecting the presence of water in its monohydrate form, which is essential for its stability. Impurities are kept to a minimum, with chloride and sulfate levels at ≤0.02%, ammonium at ≤0.1%, iron at ≤10 ppm, heavy metals at ≤10 ppm, and arsenic at ≤1 ppm. The residue on ignition is also limited to ≤0.1%, underscoring its cleanliness and suitability for sensitive applications.
Packaged typically in 25kg drums, the product can be customized to meet specific customer needs, offering flexibility for both small-scale and bulk requirements. Storage recommendations advise keeping it in a cool, dry, and well-ventilated place with the container tightly closed to preserve its integrity over time. These specifications highlight why partnering with a reputable D-(-)-Asparagine Monohydrate manufacturer in China is advantageous for consistent quality and reliability.
Applications in Pharmaceuticals
One of the primary uses of D-(-)-Asparagine Monohydrate lies in its role as an amino acid derivative in pharmaceutical intermediates. Amino acids are fundamental building blocks in drug development, and this compound’s specific D-enantiomer configuration offers unique biochemical properties. Unlike its L-counterpart, which is more common in natural proteins, the D-form is non-proteinogenic, meaning it isn’t typically incorporated into proteins but can influence metabolic pathways and cellular functions in specialized contexts.
In pharmaceutical research, D-(-)-Asparagine Monohydrate is valued for its potential in synthesizing compounds that target neurological conditions and other disorders. Its involvement in neurotransmission and cell signaling has been noted in studies exploring neuroprotection and therapeutic applications. Additionally, its high purity and low impurity profile make it an ideal candidate for producing high-quality intermediates, ensuring that the final pharmaceutical products meet regulatory standards. This makes it a critical resource for industries seeking innovative solutions from a dependable amino acid derivatives supplier in China.
Significance in Industry and Research
Beyond pharmaceuticals, D-(-)-Asparagine Monohydrate holds promise in other scientific domains. Its stability and solubility—particularly in acidic conditions—make it useful in biochemical research and microbial culture applications. For example, it has been studied for its role in wastewater treatment processes involving acrylonitrile, showcasing its versatility. The compound’s demand has been steadily increasing globally, driven by its applications and the growing need for high-purity chemical intermediates.
Researchers and manufacturers alike benefit from its consistent quality when sourced from established producers. The ability to customize packaging and ensure compliance with international standards further enhances its appeal. As industries continue to innovate, the role of D-(-)-Asparagine Monohydrate as a specialized chemical becomes increasingly prominent, supported by the expertise of a leading D-(-)-Asparagine Monohydrate manufacturer in China.
Our Additional Services
At NINGBO INNO PHARMCHEM CO.,LTD., we pride ourselves on being more than just a supplier of D-(-)-Asparagine Monohydrate. Our primary business scope encompasses the research, development, and production of fine chemicals and pharmaceutical intermediates. We specialize in continuous flow process development and equipment manufacturing, boasting our own pilot workshop and partnerships with large-scale production platforms. Our expertise spans various reaction types, including high-temperature, high-pressure, nitration, oxidation, and continuous distillation processes.
Our R&D and manufacturing services cover a wide range of products, including fine chemicals and pharmaceutical intermediates such as bromides, boric acids, thiophenes, indoles, imidazoles, thiazoles, piperazines, pyrazines, and more. We cater to production volumes ranging from 100 kg to 100 metric tons per year, focusing on processes with up to five synthetic steps. Whether you need specialized intermediates or have other chemical requirements, feel free to contact us for tailored solutions that meet your needs.
Location：