Exploring 4-Pentyloxyphenylboronic Acid: A Key Pharmaceutical Intermediate
Introduction to 4-Pentyloxyphenylboronic Acid
4-Pentyloxyphenylboronic acid, also known as 4-n-Pentyloxybenzeneboronic acid or (4-Pentyloxyphenyl)boronic acid, is an organoboron compound with the CAS number 146449-90-3. This white powder, characterized by its high purity (assay ≥98.0%) and low water content (≤0.50%), plays a significant role in the field of organic chemistry, particularly as a pharmaceutical intermediate. With a molecular formula of C11H17BO3 and a molecular weight of 208.06200, this compound exhibits unique physical and chemical properties that make it a valuable building block in drug development.
Its density is approximately 1.1±0.1 g/cm³, and it boasts a boiling point of 355.3±44.0 °C at 760 mmHg, alongside a melting point ranging from 98-100ºC. These attributes, combined with a flash point of 168.7±28.4 °C and a refractive index of 1.508, highlight its stability and suitability for various synthetic processes. In this article, we will explore the compound’s characteristics, its applications, and why it is highly sought after by industries worldwide, particularly from
4-Pentyloxyphenylboronic acid manufacturers in China.
Chemical Properties and Specifications
The chemical structure of 4-Pentyloxyphenylboronic acid includes a boronic acid group attached to a phenyl ring substituted with a pentyloxy chain. This configuration imparts specific reactivity, making it an excellent candidate for reactions such as the Suzuki-Miyauka cross-coupling, a widely used method in organic synthesis. The compound’s white powder form ensures ease of handling, while its high assay level guarantees consistent performance in laboratory and industrial settings.
For transportation, it is classified under UN Number 2924 with the proper shipping name 'FLAMMABLE LIQUID, CORROSIVE, N.O.S.' It falls under transport hazard class 3 and packing group II, indicating the need for careful handling during shipment. Storage recommendations advise keeping it in a cool, dry, and well-ventilated place with the container tightly closed to maintain its integrity over time. These specifications underscore its reliability as a chemical intermediate, especially when sourced from a reputable
4-Pentyloxyphenylboronic acid supplier in China.
Applications in Pharmaceutical Industry
The primary application of 4-Pentyloxyphenylboronic acid lies in its use as a pharmaceutical intermediate. Boronic acids are renowned for their versatility in synthesizing complex organic molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound serves as a key building block in the creation of biaryl compounds, which are essential structural components in many drugs. Its role in facilitating carbon-carbon bond formation through catalytic processes enhances its value in medicinal chemistry.
Beyond its direct use in drug synthesis, 4-Pentyloxyphenylboronic acid supports research and development efforts aimed at discovering novel therapeutic agents. Its stability and reactivity make it an ideal choice for chemists working on innovative solutions to address various health challenges. The demand for such intermediates has fueled the growth of
pharmaceutical intermediates boronic acid compounds suppliers in China, where high-quality production meets global standards.
Packaging and Storage Considerations
To ensure the compound reaches end-users in optimal condition, it is typically packaged in 25kg drums. However, flexibility in packaging allows customization based on customer requirements, a feature that enhances its accessibility for both small-scale research and large-scale manufacturing. Proper storage is critical to preserving its quality—keeping it in a cool, dry environment prevents degradation and maintains its efficacy for extended periods.
This attention to packaging and storage reflects the commitment of manufacturers to deliver a product that meets stringent industry needs. Whether you’re a researcher or a pharmaceutical producer, partnering with a trusted supplier ensures that 4-Pentyloxyphenylboronic acid arrives ready for immediate use in your projects.
Why Choose Manufacturers in China?
China has emerged as a global hub for the production of fine chemicals and pharmaceutical intermediates, including 4-Pentyloxyphenylboronic acid. The country’s advanced manufacturing infrastructure, combined with cost-effective production capabilities, makes it an attractive source for this compound.
4-Pentyloxyphenylboronic acid manufacturers in China adhere to rigorous quality control measures, ensuring that the product meets or exceeds the specified assay of ≥98.0% and water content of ≤0.50%.
Additionally, the scalability of production in China allows suppliers to cater to a wide range of order sizes, from small batches for R&D purposes to bulk quantities for industrial applications. This flexibility, paired with competitive pricing, positions Chinese suppliers as leaders in the global market. For businesses seeking a reliable
4-Pentyloxyphenylboronic acid supplier in China, the combination of quality, affordability, and availability is hard to beat.
Our Comprehensive Services
At NINGBO INNO PHARMCHEM CO.,LTD., we pride ourselves on being a leading provider of fine chemicals and pharmaceutical intermediates. Our core business encompasses the research, development, and production of compounds like 4-Pentyloxyphenylboronic acid. We specialize in continuous flow process development and the manufacturing of continuous flow equipment, supported by our in-house pilot workshop and extensive external production platforms.
Our expertise spans a variety of reaction types, including high-temperature, high-pressure, nitration, oxidation, and continuous distillation processes. We offer R&D and manufacturing services for fine chemicals and pharmaceutical intermediates such as bromides, boric acids, thiophenes, indoles, imidazoles, thiazoles, piperazines, pyrazines, and more. Our production capabilities range from 100 kg to 100 metric tons annually, focusing on products with up to five synthetic steps. If you have additional needs or inquiries, please feel free to contact us—we’re here to support your success in chemical and pharmaceutical innovation.