T-Butyldimethylchlorosilane: An Overview of Properties, Uses, and Applications
T-Butyldimethylchlorosilane: An Overview of Properties, Uses, and Applications
T-Butyldimethylchlorosilane (TBMS), also known as tert-butyl(chloro)dimethylsilane, is a versatile organosilicon compound that is widely used in various industrial applications. It is a colorless, transparent liquid with a pungent odor, and its chemical formula is C6H15ClSi. TBMS is manufactured and supplied by INNO Specialty Chemicals, a leading chemical manufacturer and supplier from China.
Properties of TBMS
TBMS is a reactive compound that readily hydrolyzes in the presence of water or moisture, producing hydrogen chloride gas and silanols. It is soluble in most organic solvents, such as chloroform, ether, benzene, and toluene, but insoluble in water. TBMS has a boiling point of 132-134°C and a flash point of 19°C, making it a flammable liquid that should be handled with care.
Uses and Applications of TBMS
TBMS is used in a wide range of industrial applications, including:
1. Silicone Synthesis: TBMS is a key intermediate in the synthesis of various silicone-based products, such as silicone oils, greases, and elastomers. It is used as a silane coupling agent to improve adhesion between the silicone and other substrates, such as glass, metal, and plastics.
2. Surface Modification: TBMS is used as a surface modifier for various materials, such as ceramics, metals, and polymers. It can be used to improve the hydrophobicity, chemical resistance, and thermal stability of the surfaces.
3. Chemical Synthesis: TBMS is used in various chemical reactions, such as Friedel-Crafts acylation, Grignard reactions, and cross-coupling reactions. It can be used as a protecting group for alcohols, amines, and carboxylic acids.
4. Pharmaceutical Synthesis: TBMS is used in the synthesis of various pharmaceutical intermediates, such as tert-butyl 4-oxopiperidine-1-carboxylate and tert-butyl (2R,3S)-3-amino-2-hydroxy-4-phenylbutanoate. It can be used as a protecting group for amines and alcohols in peptide synthesis.
5. Agrochemical Synthesis: TBMS is used in the synthesis of various agrochemicals, such as herbicides, insecticides, and fungicides. It can be used as a protecting group for amines and alcohols in the synthesis of these compounds.
Safety Precautions
TBMS is a flammable liquid that should be stored and handled in a well-ventilated area away from heat, sparks, and flames. It can cause skin, eye, and respiratory irritation, and should be used with appropriate personal protective equipment, such as gloves, goggles, and respirators. TBMS should be kept away from water or moisture, as it can hydrolyze rapidly and release hydrogen chloride gas.
Conclusion
TBMS is a valuable organosilicon compound that has a wide range of industrial applications. It is used in silicone synthesis, surface modification, chemical synthesis, pharmaceutical synthesis, and agrochemical synthesis. INNO Specialty Chemicals is a leading manufacturer and supplier of TBMS from China, providing high-quality products to customers around the world. As with all chemicals, TBMS should be handled with care and used in accordance with safety guidelines and regulations.
Location：