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Introducing 2-Chloro-4-Fluoropyridine (CAS: 34941-91-8)
Overview
2-Chloro-4-fluoropyridine, also known as 2-Chloro-4-Fluoro Pyridine, is a vital chemical compound with a wide array of applications in the pharmaceutical and agrochemical industries. This aromatic heterocyclic compound, characterized by its chlorine and fluorine substitutions on the pyridine ring, offers unique properties that make it indispensable for various synthesis processes.
Chemical Properties
- Molecular Formula: C5H4ClFN
- Molecular Weight: 135.54 g/mol
- Appearance: A colorless to pale yellow liquid
- Boiling Point: 129-130 °C
- Solubility: Soluble in organic solvents like ethanol and acetone
With its distinct electronegative groups, 2-Chloro-4-fluoropyridine exhibits enhanced reactivity, making it an ideal candidate for electrophilic aromatic substitution reactions.
Synthesis Routes
The synthesis of 2-Chloro-4-fluoropyridine can typically be achieved through various methods, including:
1. Electrophilic Aromatic Substitution: This route often involves the introduction of chlorine and fluorine into the pyridine ring via halogenation methods.
2. Nucleophilic Substitution Reactions: This method utilizes starting materials that allow for the replacement of functional groups, yielding the desired chlorofluoropyridine compound.
3. Diverse Synthetic Strategies: More sophisticated synthesis may include the use of transition metals as catalysts to facilitate reactions under milder conditions, minimizing unwanted by-products.
Quality Standards
Ningbo Inno Pharmchem adheres to stringent quality control measures to ensure that 2-Chloro-4-Fluoropyridine meets high purity standards. The product typically exhibits a purity of 98% or higher, validated by advanced analytical techniques such as HPLC and NMR. Compliance with international safety and environmental regulations is a priority for us, ensuring that our manufacturing processes are sustainable and safe.
Applications
The applications of 2-Chloro-4-Fluoropyridine are extensive:
- Pharmaceutical Intermediates: This compound serves as a crucial intermediate in the synthesis of various pharmaceuticals, particularly in the development of antimicrobial and anti-inflammatory agents.
- Agrochemical Production: Its unique properties contribute to the formulation of crop protection chemicals, enhancing agricultural efficiency and sustainability.
- Chemical Research: Used extensively in chemical research and development, 2-Chloro-4-fluoropyridine is a valuable building block for developing other complex compounds in organic synthesis.
Conclusion
As a commercially versatile compound, 2-Chloro-4-Fluoropyridine plays a significant role in both the pharmaceutical and agrochemical sectors. With a focus on reliability and quality, Ningbo Inno Pharmchem is committed to supplying this essential compound to meet the diverse needs of researchers and manufacturers alike. Embrace the future of chemical synthesis with 2-Chloro-4-fluoropyridine—your partner in innovation.