Introducing (-)-Corey Lactone: A Leading Player in Antiviral Treatments

Overview
(-)-Corey lactone, also known as entecavir, is a potent compound in the fight against viral infections, particularly hepatitis B. With a CAS number of 76704-05-7, this chemical is a key molecule recognized for its strong antiviral properties. Governed by quality standards and robust manufacturing processes, (-)-Corey lactone has become a staple in pharmaceutical development.

Chemical Properties
(-)-Corey lactone is characterized by the following chemical properties:

- Molecular formula: C₁₃H₁₈N₄O₃
- Molecular weight: 278.31 g/mol
- Structural configuration: (3aS,4R,5S,6aR)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one, which contributes to its effectiveness as an antiviral agent.

Applications
The primary application of (-)-Corey lactone is in the treatment of chronic hepatitis B virus (HBV) infections. Its mechanism of action revolves around inhibiting viral polymerase, thereby preventing the replication of the virus. This makes it an essential drug in the management of Hepatitis B, offering hope to millions of patients worldwide.

Additionally, clinical studies have shown its efficacy in treating other viral infections, making it a versatile compound in antiviral therapy.

Synthesis and Preparation
The synthesis of (-)-Corey lactone involves advanced organic chemistry techniques, ensuring high purity and yield. The standardized synthesis route enables the production of this compound at scale, while maintaining strict adherence to pharmacopoeial quality standards.

- Preparation Method: The compound undergoes a series of chemical reactions starting from readily available precursors, which are meticulously controlled to yield the desired entecavir formulation. This meticulous process ensures that the final product meets the rigorous standards for pharmaceutical use.

Quality Standards
At Ningbo Inno Pharmchem, (-)-Corey lactone is manufactured under stringent quality control measures. Our facility complies with Good Manufacturing Practices (GMP) and international quality standards, ensuring that each batch of entecavir meets the highest standards for safety and efficacy.

Conclusion
As a manufacturer and supplier of (-)-Corey lactone, Ningbo Inno Pharmchem is dedicated to providing high-quality antiviral agents to support healthcare providers in their mission to combat viral infections. Our commitment to quality, innovation, and patient care makes us a trusted partner in the pharmaceutical industry.

Explore the potential of (-)-Corey lactone, a remarkable compound that stands as a beacon of hope in the ongoing battle against hepatitis B and other viral infections.

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