Ningbo Inno Pharmchem Co., Ltd. is a leading manufacturer and supplier of high-quality specialty chemicals, intermediates, and APIs. One of their flagship products is (N-(3-Trifluoromethyl)benzenesulfonyl)alanine, a compound with numerous applications in the pharmaceutical and chemical industries. In this article, we will explore the synthetic route of this compound and analyze its feasibility for various applications.

Synthetic Route of (N-(3-Trifluoromethyl)benzenesulfonyl)alanine

(N-(3-Trifluoromethyl)benzenesulfonyl)alanine, also known as Wacker GENIOSIL XL 924, is a white crystalline powder with a molecular formula of C10H10F3NO4S. The compound is synthesized through a multi-step process starting from Cyclohexylaminomethylmethyldiethoxysilane, which is reacted with N-[[diethoxy(methyl)silyl]methyl]cyclohexanamine to form the intermediate N-(Cyclohexylaminomethyl)diethoxymethylsilane. The intermediate is then reacted with (Trifluoromethyl)benzenesulfonyl chloride and alanine methyl ester hydrochloride in the presence of a base such as sodium hydroxide to form the final product, (N-(3-Trifluoromethyl)benzenesulfonyl)alanine.

Feasibility Analysis of (N-(3-Trifluoromethyl)benzenesulfonyl)alanine

(N-(3-Trifluoromethyl)benzenesulfonyl)alanine has several applications in the pharmaceutical and chemical industries. One of the primary uses of this compound is as a reagent for peptide synthesis. The compound can be used as an activating agent for carboxylic acids, which are commonly used in peptide synthesis. The trifluoromethylsulfonyl group on the compound enhances the reactivity of carboxylic acids, making it a useful reagent for peptide synthesis.

Another application of (N-(3-Trifluoromethyl)benzenesulfonyl)alanine is as a building block for the synthesis of various pharmaceutical compounds. The compound has been used as a key intermediate for the synthesis of drugs such as rufinamide, which is used to treat seizures in patients with Lennox-Gastaut syndrome. The compound has also been used in the synthesis of agrochemicals and other specialty chemicals.

(N-(3-Trifluoromethyl)benzenesulfonyl)alanine is a highly versatile compound with a wide range of applications. Its unique properties make it a valuable tool for researchers and scientists in the pharmaceutical and chemical industries.

Conclusion

Ningbo Inno Pharmchem Co., Ltd. is a reputable manufacturer and supplier of (N-(3-Trifluoromethyl)benzenesulfonyl)alanine, a compound with numerous applications in the pharmaceutical and chemical industries. The synthetic route of this compound involves a multi-step process starting from Cyclohexylaminomethylmethyldiethoxysilane, which is reacted with N-[[diethoxy(methyl)silyl]methyl]cyclohexanamine to form the intermediate N-(Cyclohexylaminomethyl)diethoxymethylsilane. The intermediate is then reacted with (Trifluoromethyl)benzenesulfonyl chloride and alanine methyl ester hydrochloride in the presence of a base such as sodium hydroxide to form the final product, (N-(3-Trifluoromethyl)benzenesulfonyl)alanine. The compound has several applications in the pharmaceutical and chemical industries, including as a reagent for peptide synthesis and a building block for the synthesis of various pharmaceutical compounds. Ningbo Inno Pharmchem Co., Ltd. is committed to providing high-quality products and exceptional customer service to its clients worldwide. Contact them today to learn more about (N-(3-Trifluoromethyl)benzenesulfonyl)alanine and their other specialty chemicals and APIs.

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