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(E)-Trimethylsilyl N-(trimethylsilyl)acetimidate: Synthesis and Application in Organic Chemistry by a Leading Manufacturer
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N,O-Bistrimethylsilylacetamide CAS:10416-59-8 manufacturer


Organic chemistry is an important field in the chemical industry, with applications in various sectors such as pharmaceuticals, polymers, and agrochemicals. To create efficient and effective organic compounds, researchers rely on high-quality reagents, such as (E)-trimethylsilyl N-(trimethylsilyl)acetimidate. This compound is manufactured by Ningbo Inno Pharmchem Co., Ltd., a leading manufacturer and supplier of fine chemicals.

Ningbo Inno Pharmchem Co., Ltd. has a reputation for producing high-quality chemicals for the chemical industry. The company's expertise in synthesizing and manufacturing fine chemicals has made it a trusted partner for many businesses. In particular, the company's (E)-trimethylsilyl N-(trimethylsilyl)acetimidate is a staple in organic chemistry laboratories around the world. This compound is widely used in the synthesis of various organic compounds, including peptides, amino acids, and heterocyclic compounds.

(E)-Trimethylsilyl N-(trimethylsilyl)acetimidate is a derivative of N,O-bis(trimethylsilyl)acetamide, also known as N,O-bistrimethylsilylacetamide (BSA). BSA is a popular reagent used in organic synthesis to protect amides and carboxylic acids. (E)-Trimethylsilyl N-(trimethylsilyl)acetimidate is a versatile reagent that is used to synthesize a variety of compounds, including β-keto esters, β-keto amides, and β-keto nitriles.

The synthesis of (E)-trimethylsilyl N-(trimethylsilyl)acetimidate is a complex process that requires expertise and precision. Ningbo Inno Pharmchem Co., Ltd. has a state-of-the-art factory equipped with advanced technologies and equipment to produce high-quality chemicals. The company's production process involves the reaction of N,O-bis(trimethylsilyl)acetamide with trimethylsilyl chloride in the presence of a base. The resulting product is (E)-trimethylsilyl N-(trimethylsilyl)acetimidate, a colorless liquid with a boiling point of 140-141°C.

(E)-Trimethylsilyl N-(trimethylsilyl)acetimidate has many applications in organic chemistry. One of its main uses is in the synthesis of β-keto esters. These compounds are important intermediates in the synthesis of many natural products, such as vitamins, antibiotics, and steroids. (E)-Trimethylsilyl N-(trimethylsilyl)acetimidate is used to convert carboxylic acids to their corresponding β-keto esters, which can then be used in further reactions.

Another important application of (E)-trimethylsilyl N-(trimethylsilyl)acetimidate is in the synthesis of β-keto amides. These compounds are used in the production of pharmaceuticals, such as non-steroidal anti-inflammatory drugs (NSAIDs). (E)-Trimethylsilyl N-(trimethylsilyl)acetimidate is used to convert carboxylic acids to their corresponding β-keto amides, which can then be used in further reactions.

(E)-Trimethylsilyl N-(trimethylsilyl)acetimidate is also used in the synthesis of β-keto nitriles. These compounds are important intermediates in the production of agrochemicals, such as herbicides and insecticides. (E)-Trimethylsilyl N-(trimethylsilyl)acetimidate is used to convert carboxylic acids to their corresponding β-keto nitriles, which can then be used in further reactions.

In conclusion, (E)-trimethylsilyl N-(trimethylsilyl)acetimidate is a versatile reagent that has many applications in organic chemistry. Ningbo Inno Pharmchem Co., Ltd. is a leading manufacturer and supplier of this important compound. With its state-of-the-art factory and expertise in fine chemical synthesis, the company is able to produce high-quality (E)-trimethylsilyl N-(trimethylsilyl)acetimidate that meets the needs of researchers and businesses in the chemical industry.
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